TrialsConnect is a system that bridges researchers and participants in a clinical trial to improve participant education, communication, and engagement. Researchers can easily manage from small scale of several trial participants to large scale of hundreds trial participants. TrialsConnect is a cloud system that allows researchers to access the tools from anywhere, anytime. Researchers can effortlessly create schedule, manage appointment, improve retension, deliver educational information and reports, and exchange multimedia messages with participants. For participants, a mobile application targets for both iOS and Android systems allows them to schedule an appointment, communicate, receive the information and explore food or lodging information around the research facilities all on their mobile devices. Participants are encouraged to engage in the trial with our unique reward system.